I was asked to have a look at an Audi A4 with a noisy driver's window recently, the window emitted a metallic grinding sound when opened and closed. From other reports on the Internet it appeared that a replacement drive mechanism was the cure. This involved a complete strip down of the drivers door.
The cable driven mechanism was replaced with a new Audi part, see below, and the door reassembled.
Total time for the job was two hours and after reinitialising the one shot we now have a smooth, quiet driver's window. Investigation of the old winding mechanism revealed the source of the noise; the cable inside the spool had a kink which was fouling the rest of the cable as it wound up and down. It was also wearing the nylon outer spool.